Altered mechanisms of protein synthesis in frontal cortex in Alzheimer disease and a mouse model

Expression of the nucleolar chaperones nucleolin (NCL) and nucleophosmin (NPM1), upstream binding transcription factor (UBTF), rRNA18S, rRNA28S, and several genes encoding ribosomal proteins (RPs) is decreased in frontal cortex area 8 at advanced stages of Alzheimer’s disease (AD). This is accompani...

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Publicat a:Am J Neurodegener Dis
Autors principals: Garcia-Esparcia, Paula, Sideris-Lampretsas, Georgios, Hernandez-Ortega, Karina, Grau-Rivera, Oriol, Sklaviadis, Theodoros, Gelpi, Ellen, Ferrer, Isidro
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498849/
https://ncbi.nlm.nih.gov/pubmed/28695061
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