Altered mechanisms of protein synthesis in frontal cortex in Alzheimer disease and a mouse model

Expression of the nucleolar chaperones nucleolin (NCL) and nucleophosmin (NPM1), upstream binding transcription factor (UBTF), rRNA18S, rRNA28S, and several genes encoding ribosomal proteins (RPs) is decreased in frontal cortex area 8 at advanced stages of Alzheimer’s disease (AD). This is accompani...

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Detalhes bibliográficos
Publicado no:Am J Neurodegener Dis
Main Authors: Garcia-Esparcia, Paula, Sideris-Lampretsas, Georgios, Hernandez-Ortega, Karina, Grau-Rivera, Oriol, Sklaviadis, Theodoros, Gelpi, Ellen, Ferrer, Isidro
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498849/
https://ncbi.nlm.nih.gov/pubmed/28695061
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