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Purine‐related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology

Adenosine, hypoxanthine, xanthine, guanosine and inosine levels were assessed by HPLC, and the activity of related enzymes 5′‐nucleotidase (5′‐NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) measured in frontal (FC), parietal (PC) and temporal (TC) cortices at different stag...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Alonso‐Andrés, Patricia, Albasanz, José Luis, Ferrer, Isidro, Martín, Mairena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028663/
https://ncbi.nlm.nih.gov/pubmed/29363833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12592
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