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Purine‐related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology

Adenosine, hypoxanthine, xanthine, guanosine and inosine levels were assessed by HPLC, and the activity of related enzymes 5′‐nucleotidase (5′‐NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) measured in frontal (FC), parietal (PC) and temporal (TC) cortices at different stag...

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Bibliografski detalji
Izdano u:Brain Pathol
Glavni autori: Alonso‐Andrés, Patricia, Albasanz, José Luis, Ferrer, Isidro, Martín, Mairena
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028663/
https://ncbi.nlm.nih.gov/pubmed/29363833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12592
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