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Purine‐related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology

Adenosine, hypoxanthine, xanthine, guanosine and inosine levels were assessed by HPLC, and the activity of related enzymes 5′‐nucleotidase (5′‐NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) measured in frontal (FC), parietal (PC) and temporal (TC) cortices at different stag...

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Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Alonso‐Andrés, Patricia, Albasanz, José Luis, Ferrer, Isidro, Martín, Mairena
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028663/
https://ncbi.nlm.nih.gov/pubmed/29363833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12592
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