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Purine‐related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology

Adenosine, hypoxanthine, xanthine, guanosine and inosine levels were assessed by HPLC, and the activity of related enzymes 5′‐nucleotidase (5′‐NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) measured in frontal (FC), parietal (PC) and temporal (TC) cortices at different stag...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Alonso‐Andrés, Patricia, Albasanz, José Luis, Ferrer, Isidro, Martín, Mairena
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028663/
https://ncbi.nlm.nih.gov/pubmed/29363833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12592
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