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Novel T cells with improved in vivo anti-tumor activity generated by RNA electroporation

The generation of T cells with maximal anti-tumor activities will significantly impact the field of T-cell-based adoptive immunotherapy. In this report, we found that OKT3/IL-2-stimulated T cells were phenotypically more heterogeneous, with enhanced anti-tumor activity in vitro and when locally admi...

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Dettagli Bibliografici
Pubblicato in:Protein Cell
Autori principali: Liu, Xiaojun, Jiang, Shuguang, Fang, Chongyun, Li, Hua, Zhang, Xuhua, Zhang, Fuqin, June, Carl H., Zhao, Yangbing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498341/
https://ncbi.nlm.nih.gov/pubmed/28523432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0422-6
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