ロード中...

Multiplex genome editing to generate universal CAR T cells resistant to PD1 inhibition

PURPOSE: Using gene-disrupted allogeneic T cells as universal effector cells provides an alternative to and potentially improves current chimeric antigen receptor (CAR) T cell therapy against cancers and infectious diseases. EXPERIMENTAL DESIGN: The CRISPR/Cas9 system has recently emerged as a simpl...

詳細記述

保存先:
書誌詳細
出版年:Clin Cancer Res
主要な著者: Ren, Jiangtao, Liu, Xiaojun, Fang, Chongyun, Jiang, Shuguang, June, Carl H., Zhao, Yangbing
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413401/
https://ncbi.nlm.nih.gov/pubmed/27815355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1300
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!