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A versatile system for rapid multiplex genome-edited CAR T cell generation

The therapeutic potential of CRISPR system has already been demonstrated in many instances and begun to overlap with the rapidly expanding field of cancer immunotherapy, especially on the production of genetically modified T cell receptor or chimeric antigen receptor (CAR) T cells. Efficient genomic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ren, Jiangtao, Zhang, Xuhua, Liu, Xiaojun, Fang, Chongyun, Jiang, Shuguang, June, Carl H., Zhao, Yangbing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370017/
https://ncbi.nlm.nih.gov/pubmed/28199983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15218
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