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The DBA/2J haplotype on distal chromosome 2 reduces Mertk expression, restricts efferocytosis and increases susceptibility to atherosclerosis
OBJECTIVE: Arch atherosclerosis 4 (Aath4) is a quantitative trait locus for atherosclerotic plaque formation in the inner curve of the aortic arch previously identified in an F2 cross of Apoe(−/−) mice on DBA/2J and 129S6 backgrounds. Mertk, coding for a ligand-activated transmembrane tyrosine kinas...
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| Veröffentlicht in: | Arterioscler Thromb Vasc Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5497749/ https://ncbi.nlm.nih.gov/pubmed/28473436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309522 |
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