Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice

The genetic background of apolipoprotein E (apoE) deficient mice influences atherosclerotic plaque development. We previously reported three quantitative trait loci (QTL), Aath1–Aath3, that affect aortic arch atherosclerosis independently of those in the aortic root in a cross between C57BL6 apoEKO...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kayashima, Yukako, Makhanova, Natalia A., Matsuki, Kota, Tomita, Hirofumi, Bennett, Brian J., Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331513/
https://ncbi.nlm.nih.gov/pubmed/25689165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117478
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