Cellular differentiation state modulates the mRNA export activity of SR proteins

SR proteins function in nuclear pre-mRNA processing, mRNA export, and translation. To investigate their cellular dynamics, we developed a quantitative assay, which detects differences in nucleocytoplasmic shuttling among seven canonical SR protein family members. As expected, SRSF2 and SRSF5 shuttle...

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Publicado en:J Cell Biol
Autores principales: Botti, Valentina, McNicoll, François, Steiner, Michaela C., Richter, Florian M., Solovyeva, Anfisa, Wegener, Marius, Schwich, Oliver D., Poser, Ina, Zarnack, Kathi, Wittig, Ilka, Neugebauer, Karla M., Müller-McNicoll, Michaela
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496613/
https://ncbi.nlm.nih.gov/pubmed/28592444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610051
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