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Fractionation iCLIP detects persistent SR protein binding to conserved, retained introns in chromatin, nucleoplasm and cytoplasm

RNA binding proteins (RBPs) regulate the lives of all RNAs from transcription, processing, and function to decay. How RNA–protein interactions change over time and space to support these roles is poorly understood. Towards this end, we sought to determine how two SR proteins—SRSF3 and SRSF7, regulat...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Brugiolo, Mattia, Botti, Valentina, Liu, Na, Müller-McNicoll, Michaela, Neugebauer, Karla M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737842/
https://ncbi.nlm.nih.gov/pubmed/28977534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx671
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