The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes

BACKGROUND: The SR proteins comprise a family of essential, structurally related RNA binding proteins. The complexity of their RNA targets and specificity of RNA recognition in vivo is not well understood. Here we use iCLIP to globally analyze and compare the RNA binding properties of two SR protein...

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Detalhes bibliográficos
Main Authors: Änkö, Minna-Liisa, Müller-McNicoll, Michaela, Brandl, Holger, Curk, Tomaz, Gorup, Crtomir, Henry, Ian, Ule, Jernej, Neugebauer, Karla M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439968/
https://ncbi.nlm.nih.gov/pubmed/22436691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-3-r17
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