New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

BACKGROUND: A DNA-human Ad5 (HuAd5) prime-boost malaria vaccine has been shown to protect volunteers against a controlled human malaria infection. The potency of this vaccine, however, appeared to be affected by the presence of pre-existing immunity against the HuAd5 vector. Since HuAd5 seroprevalen...

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Foilsithe in:Malar J
Main Authors: Limbach, Keith, Stefaniak, Maureen, Chen, Ping, Patterson, Noelle B., Liao, Grant, Weng, Shaojie, Krepkiy, Svetlana, Ekberg, Greg, Torano, Holly, Ettyreddy, Damodar, Gowda, Kalpana, Sonawane, Sharvari, Belmonte, Arnel, Abot, Esteban, Sedegah, Martha, Hollingdale, Michael R., Moormann, Ann, Vulule, John, Villasante, Eileen, Richie, Thomas L., Brough, Douglas E., Bruder, Joseph T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496260/
https://ncbi.nlm.nih.gov/pubmed/28673287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1911-z
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