Identification of two new protective pre-erythrocytic malaria vaccine antigen candidates

Por Limbach, Keith, Aguiar, Joao, Gowda, Kalpana, Patterson, Noelle, Abot, Esteban, Sedegah, Martha, Sacci, John, Richie, Thomas
Publicado em 2011

Controlled Human Malaria Infection (CHMI) differentially affects cell-mediated and antibody responses to CSP and AMA1 induced by adenovirus vaccines with and without DNA-priming

Por Sedegah, Martha, Hollingdale, Michael R, Farooq, Fouzia, Ganeshan, Harini, Belmonte, Maria, Huang, Jun, Abot, Esteban, Limbach, Keith, Chuang, Ilin, Tamminga, Cindy, Epstein, Judith E, Villasante, Eileen
Publicado no Hum Vaccin Immunother (2015)

Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

Por Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L., Doolan, Denise L.
Publicado em 2012

Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

Por Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L., Doolan, Denise L.
Publicado em 2012

A Plasmodium vivax Plasmid DNA- and Adenovirus-Vectored Malaria Vaccine Encoding Blood-Stage Antigens AMA1 and MSP1(42) in a Prime/Boost Heterologous Immunization Regimen Partially...

Por Obaldia, Nicanor, Stockelman, Michael G., Otero, William, Cockrill, Jennifer A., Ganeshan, Harini, Abot, Esteban N., Zhang, Jianfeng, Limbach, Keith, Charoenvit, Yupin, Doolan, Denise L., Tang, De-chu C., Richie, Thomas L.
Publicado no Clin Vaccine Immunol (2017)

Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes

Por Sedegah, Martha, Peters, Bjoern, Hollingdale, Michael R., Ganeshan, Harini D., Huang, Jun, Farooq, Fouzia, Belmonte, Maria N., Belmonte, Arnel D., Limbach, Keith J., Diggs, Carter, Soisson, Lorraine, Chuang, Ilin, Villasante, Eileen D.
Publicado no PLoS One (2016)

Correction: Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes

Por Sedegah, Martha, Peters, Bjoern, Hollingdale, Michael R., Ganeshan, Harini D., Huang, Jun, Farooq, Fouzia, Belmonte, Maria N., Belmonte, Arnel D., Limbach, Keith J., Diggs, Carter, Soisson, Lorraine, Chuang, Ilin, Villasante, Eileen D.
Publicado no PLoS One (2016)

Sterile Immunity to Malaria after DNA Prime/Adenovirus Boost Immunization Is Associated with Effector Memory CD8+T Cells Targeting AMA1 Class I Epitopes

Por Sedegah, Martha, Hollingdale, Michael R., Farooq, Fouzia, Ganeshan, Harini, Belmonte, Maria, Kim, Yohan, Peters, Bjoern, Sette, Alessandro, Huang, Jun, McGrath, Shannon, Abot, Esteban, Limbach, Keith, Shi, Meng, Soisson, Lorraine, Diggs, Carter, Chuang, Ilin, Tamminga, Cindy, Epstein, Judith E., Villasante, Eileen, Richie, Thomas L.
Publicado em 2014

Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

Por Aguiar, Joao C., Bolton, Jessica, Wanga, Joyce, Sacci, John B., Iriko, Hideyuki, Mazeika, Julie K., Han, Eun-Taek, Limbach, Keith, Patterson, Noelle B., Sedegah, Martha, Cruz, Ann-Marie, Tsuboi, Takafumi, Hoffman, Stephen L., Carucci, Daniel, Hollingdale, Michael R., Villasante, Eileen D., Richie, Thomas L.
Publicado no PLoS One (2015)

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

Por Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, Valencia, Anais, Singh, Priti, Aguiar, Joao, Limbach, Keith, Kamrud, Kurt I., Rayner, Jonathan, Smith, Jonathan, Bruder, Joseph T., King, C. Richter, Tsuboi, Takafumi, Takeo, Satoru, Endo, Yaeta, Doolan, Denise L., Richie, Thomas L., Weiss, Walter R.
Publicado em 2009

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

Por Limbach, Keith, Stefaniak, Maureen, Chen, Ping, Patterson, Noelle B., Liao, Grant, Weng, Shaojie, Krepkiy, Svetlana, Ekberg, Greg, Torano, Holly, Ettyreddy, Damodar, Gowda, Kalpana, Sonawane, Sharvari, Belmonte, Arnel, Abot, Esteban, Sedegah, Martha, Hollingdale, Michael R., Moormann, Ann, Vulule, John, Villasante, Eileen, Richie, Thomas L., Brough, Douglas E., Bruder, Joseph T.
Publicado no Malar J (2017)

Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled hum...

Por Tamminga, Cindy, Sedegah, Martha, Maiolatesi, Santina, Fedders, Charlotte, Reyes, Sharina, Reyes, Anatalio, Vasquez, Carlos, Alcorta, Yolanda, Chuang, Ilin, Spring, Michele, Kavanaugh, Michael, Ganeshan, Harini, Huang, Jun, Belmonte, Maria, Abot, Esteban, Belmonte, Arnel, Banania, JoGlenna, Farooq, Fouzia, Murphy, Jittawadee, Komisar, Jack, Richie, Nancy O, Bennett, Jason, Limbach, Keith, Patterson, Noelle B, Bruder, Joseph T, Shi, Meng, Miller, Edward, Dutta, Sheetij, Diggs, Carter, Soisson, Lorraine A, Hollingdale, Michael R, Epstein, Judith E, Richie, Thomas L
Publicado em 2013

Adenovirus 5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part A: Safety and Immunogenicity in Seronegative Adults

Por Sedegah, Martha, Tamminga, Cindy, McGrath, Shannon, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J., Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Manohar, Nalini, Richie, Nancy O., Wood, Chloe, Long, Carole A., Regis, David, Williams, Francis T., Shi, Meng, Chuang, Ilin, Spring, Michele, Epstein, Judith E., Mendoza-Silveiras, Jose, Limbach, Keith, Patterson, Noelle B., Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Soisson, Lorraine, Diggs, Carter, Carucci, Daniel, Dutta, Sheetij, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado em 2011

Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component

Por Tamminga, Cindy, Sedegah, Martha, Regis, David, Chuang, Ilin, Epstein, Judith E., Spring, Michele, Mendoza-Silveiras, Jose, McGrath, Shannon, Maiolatesi, Santina, Reyes, Sharina, Steinbeiss, Victoria, Fedders, Charlotte, Smith, Kathryn, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J., Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Murphy, Jittawadee, Komisar, Jack, Williams, Jackie, Shi, Meng, Brambilla, Donald, Manohar, Nalini, Richie, Nancy O., Wood, Chloe, Limbach, Keith, Patterson, Noelle B., Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Diggs, Carter, Soisson, Lorraine, Carucci, Daniel, Levine, Gail, Dutta, Sheetij, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado em 2011

Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falcip...

Por Richie, Thomas L., Charoenvit, Yupin, Wang, Ruobing, Epstein, Judith E., Hedstrom, Richard C., Kumar, Sanjai, Luke, Thomas C., Freilich, Daniel A., Aguiar, Joao C., Sacci, Jr., John B., Sedegah, Martha, Nosek, Jr., Ronald A., De La Vega, Patricia, Berzins, Mara P., Majam, Victoria F., Abot, Esteban N., Ganeshan, Harini, Richie, Nancy O., Banania, Jo Glenna, Baraceros, Maria Fe B., Geter, Tanya G., Mere, Robin, Bebris, Lolita, Limbach, Keith, Hickey, Bradley W., Lanar, David E., Ng, Jennifer, Shi, Meng, Hobart, Peter M., Norman, Jon A., Soisson, Lorraine A., Hollingdale, Michael R., Rogers, William O., Doolan, Denise L., Hoffman, Stephen L.
Publicado em 2012

DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

Por Chuang, Ilin, Sedegah, Martha, Cicatelli, Susan, Spring, Michele, Polhemus, Mark, Tamminga, Cindy, Patterson, Noelle, Guerrero, Melanie, Bennett, Jason W., McGrath, Shannon, Ganeshan, Harini, Belmonte, Maria, Farooq, Fouzia, Abot, Esteban, Banania, Jo Glenna, Huang, Jun, Newcomer, Rhonda, Rein, Lisa, Litilit, Dianne, Richie, Nancy O., Wood, Chloe, Murphy, Jittawadee, Sauerwein, Robert, Hermsen, Cornelus C., McCoy, Andrea J., Kamau, Edwin, Cummings, James, Komisar, Jack, Sutamihardja, Awalludin, Shi, Meng, Epstein, Judith E., Maiolatesi, Santina, Tosh, Donna, Limbach, Keith, Angov, Evelina, Bergmann-Leitner, Elke, Bruder, Joseph T., Doolan, Denise L., King, C. Richter, Carucci, Daniel, Dutta, Sheetij, Soisson, Lorraine, Diggs, Carter, Hollingdale, Michael R., Ockenhouse, Christian F., Richie, Thomas L.
Publicado em 2013