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New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model
BACKGROUND: A DNA-human Ad5 (HuAd5) prime-boost malaria vaccine has been shown to protect volunteers against a controlled human malaria infection. The potency of this vaccine, however, appeared to be affected by the presence of pre-existing immunity against the HuAd5 vector. Since HuAd5 seroprevalen...
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Publicado no: | Malar J |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496260/ https://ncbi.nlm.nih.gov/pubmed/28673287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1911-z |
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