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HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
Hemodynamic forces regulate vascular functions. Disturbed flow (DF) occurs in arterial bifurcations and curvatures, activates endothelial cells (ECs), and results in vascular inflammation and ultimately atherosclerosis. However, how DF alters EC metabolism, and whether resulting metabolic changes in...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495571/ https://ncbi.nlm.nih.gov/pubmed/28556776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25217 |
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