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Interleukin-6 regulates iron-related proteins through c-Jun N-terminal kinase activation in BV2 microglial cell lines

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DA) neurons in the substantia nigra (SN) and subsequent DA depletion in the striatum. Microglia activation and nigral iron accumulation play important roles in the pathogenesis of PD. Activated...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhou, Shida, Du, Xinxing, Xie, Junxia, Wang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495437/
https://ncbi.nlm.nih.gov/pubmed/28672025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180464
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