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Interleukin-6 regulates iron-related proteins through c-Jun N-terminal kinase activation in BV2 microglial cell lines

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DA) neurons in the substantia nigra (SN) and subsequent DA depletion in the striatum. Microglia activation and nigral iron accumulation play important roles in the pathogenesis of PD. Activated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Shida, Du, Xinxing, Xie, Junxia, Wang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495437/
https://ncbi.nlm.nih.gov/pubmed/28672025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180464
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