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Role of Akt and c-Jun N-terminal Kinase 2 in Apoptosis Induced by Interleukin-4 Deprivation

We have shown previously that interleukin-4 (IL-4) protects TS1αβ cells from apoptosis, but very little is known about the mechanism by which IL-4 exerts this effect. We found that Akt activity, which is dependent on phosphatidylinositol 3 kinase, is reduced in IL-4-deprived TS1αβ cells. Overexpress...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Principais autores: Cerezo, Ana, Martínez-A, Carlos, Lanzarot, Diego, Fischer, Siegmund, Franke, Thomas F., Rebollo, Angelita
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Cell Biology 1998
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9802900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.11.3107
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