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Huntington’s Disease: Mechanisms of Pathogenesis and Therapeutic Strategies

Huntington's disease is a late-onset neurodegenerative disease caused by a CAG trinucleotide repeat in the gene encoding the huntingtin protein. Despite its well-defined genetic origin, the molecular and cellular mechanisms underlying the disease are unclear and complex. Here, we review some of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cold Spring Harb Perspect Med
Egile Nagusiak: Jimenez-Sanchez, Maria, Licitra, Floriana, Underwood, Benjamin R., Rubinsztein, David C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495055/
https://ncbi.nlm.nih.gov/pubmed/27940602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024240
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