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Huntington’s Disease: Mechanisms of Pathogenesis and Therapeutic Strategies
Huntington's disease is a late-onset neurodegenerative disease caused by a CAG trinucleotide repeat in the gene encoding the huntingtin protein. Despite its well-defined genetic origin, the molecular and cellular mechanisms underlying the disease are unclear and complex. Here, we review some of...
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| 出版年: | Cold Spring Harb Perspect Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495055/ https://ncbi.nlm.nih.gov/pubmed/27940602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024240 |
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