Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of a hTERT promoter at the 3′-side of the transgene

Reduced expression in immortalized cells (REIC)/Dickkopf-3 (Dkk-3) overexpression, induced using an adenovirus (Ad)-REIC, has been revealed to have a dramatic therapeutic effect on multiple types of cancer. To achieve an improved therapeutic effect from Ad-REIC on cancer, our group previously develo...

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Udgivet i:Oncol Lett
Main Authors: Putranto, Endy Widya, Kinoshita, Rie, Watanabe, Masami, Sadahira, Takuya, Murata, Hitoshi, Yamamoto, Ken-Ichi, Futami, Junichiro, Kataoka, Ken, Inoue, Yusuke, Winarsa Ruma, I. Made, Sumardika, I. Wayan, Youyi, Chen, Kubo, Miyoko, Sakaguchi, Yoshihiko, Saito, Kenji, Nasu, Yasutomo, Kumon, Hiromi, Huh, Nam-Ho, Sakaguchi, Masakiyo
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494794/
https://ncbi.nlm.nih.gov/pubmed/28693271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6201
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