Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK1

The third member of the Dickkopf family (DKK-3), also known as reduced expression in immortalized cells (REIC), is a tumor suppressor present in a variety of tumor cells. Regarding the regulation of the Wnt/β-catenin signaling pathway, exogenous DKK-1 and DKK-2 are reported to inhibit Wnt signaling...

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Vydáno v:Oncol Lett
Hlavní autoři: Xu, Jiaqi, Sadahira, Takuya, Kinoshita, Rie, Li, Shun-Ai, Huang, Peng, Wada, Koichiro, Araki, Motoo, Ochiai, Kazuhiko, Noguchi, Hirofumi, Sakaguchi, Masakiyo, Nasu, Yasutomo, Watanabe, Masami
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652141/
https://ncbi.nlm.nih.gov/pubmed/29098038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6833
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