Overexpression of REIC/Dkk-3 in Normal Fibroblasts Suppresses Tumor Growth via Induction of Interleukin-7

We previously showed that the tumor suppressor gene REIC/Dkk-3, when overexpressed by an adenovirus (Ad-REIC), exhibited a dramatic therapeutic effect on human cancers through a mechanism triggered by endoplasmic reticulum stress. Adenovirus vectors show no target cell specificity and thus may elici...

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Detalhes bibliográficos
Main Authors: Sakaguchi, Masakiyo, Kataoka, Ken, Abarzua, Fernando, Tanimoto, Ryuta, Watanabe, Masami, Murata, Hitoshi, Than, Swe Swe, Kurose, Kaoru, Kashiwakura, Yuji, Ochiai, Kazuhiko, Nasu, Yasutomo, Kumon, Hiromi, Huh, Nam-ho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682872/
https://ncbi.nlm.nih.gov/pubmed/19279003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808002200
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