Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer

OBJECTIVES: REIC/Dkk-3 is down-regulated in a broad range of human cancer cells and is considered to function as a tumor suppressor. We previously reported that REIC/Dkk-3-expressing adenovirus vector (Ad-REIC) induced endoplasmic reticulum (ER) stress and cancer-specific apoptosis in human prostate...

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Main Authors: Shien, Kazuhiko, Tanaka, Norimitsu, Watanabe, Masami, Soh, Junichi, Sakaguchi, Masakiyo, Matsuo, Keitaro, Yamamoto, Hiromasa, Furukawa, Masashi, Asano, Hiroaki, Tsukuda, Kazunori, Nasu, Yasutomo, Huh, Nam-Ho, Miyoshi, Shinichiro, Kumon, Hiromi, Toyooka, Shinichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912155/
https://ncbi.nlm.nih.gov/pubmed/24498395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087900
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