A super gene expression system enhances the anti-glioma effects of adenovirus-mediated REIC/Dkk-3 gene therapy

Reduced expression in immortalized cells/Dickkopf-3 (REIC/Dkk-3) is a tumor suppressor and therapeutic gene in many human cancers. Recently, an adenovirus REIC vector with the super gene expression system (Ad-SGE-REIC) was developed to increase REIC/Dkk-3 expression and enhance therapeutic effects c...

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Pubblicato in:Sci Rep
Autori principali: Oka, Tetsuo, Kurozumi, Kazuhiko, Shimazu, Yosuke, Ichikawa, Tomotsugu, Ishida, Joji, Otani, Yoshihiro, Shimizu, Toshihiko, Tomita, Yusuke, Sakaguchi, Masakiyo, Watanabe, Masami, Nasu, Yasutomo, Kumon, Hiromi, Date, Isao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022040/
https://ncbi.nlm.nih.gov/pubmed/27625116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33319
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