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Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae

The yeast Saccharomyces cerevisiae is widely used to produce biopharmaceutical proteins. However, the limited capacity of the secretory pathway may reduce its productivity. Here, we increased the secretion of a heterologous α-amylase, a model protein used for studying the protein secretory pathway i...

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Publicat a:Appl Environ Microbiol
Autors principals: Bao, Jichen, Huang, Mingtao, Petranovic, Dina, Nielsen, Jens
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494634/
https://ncbi.nlm.nih.gov/pubmed/28476767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03400-16
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