Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion

Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and low productivities associated with their production in mam...

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Udgivet i:Microb Cell Fact
Main Authors: Wang, Yanyan, Li, Xiaowei, Chen, Xin, Nielsen, Jens, Petranovic, Dina, Siewers, Verena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278646/
https://ncbi.nlm.nih.gov/pubmed/34261490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01624-0
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