Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion

Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and low productivities associated with their production in mam...

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Bibliographic Details
Published in:Microb Cell Fact
Main Authors: Wang, Yanyan, Li, Xiaowei, Chen, Xin, Nielsen, Jens, Petranovic, Dina, Siewers, Verena
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278646/
https://ncbi.nlm.nih.gov/pubmed/34261490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01624-0
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