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Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is widely used to produce biopharmaceutical proteins. However, the limited capacity of the secretory pathway may reduce its productivity. Here, we increased the secretion of a heterologous α-amylase, a model protein used for studying the protein secretory pathway i...
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| Publié dans: | Appl Environ Microbiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494634/ https://ncbi.nlm.nih.gov/pubmed/28476767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03400-16 |
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