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Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae

The yeast Saccharomyces cerevisiae is widely used to produce biopharmaceutical proteins. However, the limited capacity of the secretory pathway may reduce its productivity. Here, we increased the secretion of a heterologous α-amylase, a model protein used for studying the protein secretory pathway i...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Bao, Jichen, Huang, Mingtao, Petranovic, Dina, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494634/
https://ncbi.nlm.nih.gov/pubmed/28476767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03400-16
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