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Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

The yeast Saccharomyces cerevisiae is widely used as a cell factory to produce recombinant proteins. However, S. cerevisiae naturally secretes only a few proteins, such as invertase and the mating alpha factor, and its secretory capacity is limited. It has been reported that engineering protein ante...

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Detalhes bibliográficos
Publicado no:AMB Express
Main Authors: Bao, Jichen, Huang, Mingtao, Petranovic, Dina, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847638/
https://ncbi.nlm.nih.gov/pubmed/29532188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-018-0571-x
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