Neurotrophin 3 upregulates proliferation and collagen production in human aortic valve interstitial cells: a potential role in aortic valve sclerosis

Calcific aortic valve disease (CAVD) is a leading cardiovascular disorder in the elderly. Diseased aortic valves are characterized by sclerosis (fibrosis) and nodular calcification. Sclerosis, an early pathological change, is caused by aortic valve interstitial cell (AVIC) proliferation and overprod...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Yao, Qingzhou, Song, Rui, Ao, Lihua, Cleveland, Joseph C., Fullerton, David A., Meng, Xianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494589/
https://ncbi.nlm.nih.gov/pubmed/28356268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00292.2016
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