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Neurotrophin 3 upregulates proliferation and collagen production in human aortic valve interstitial cells: a potential role in aortic valve sclerosis

Calcific aortic valve disease (CAVD) is a leading cardiovascular disorder in the elderly. Diseased aortic valves are characterized by sclerosis (fibrosis) and nodular calcification. Sclerosis, an early pathological change, is caused by aortic valve interstitial cell (AVIC) proliferation and overprod...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Yao, Qingzhou, Song, Rui, Ao, Lihua, Cleveland, Joseph C., Fullerton, David A., Meng, Xianzhong
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494589/
https://ncbi.nlm.nih.gov/pubmed/28356268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00292.2016
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