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A genome editing approach to study cancer stem cells in human tumors
The analysis of stem cell hierarchies in human cancers has been hampered by the impossibility of identifying or tracking tumor cell populations in an intact environment. To overcome this limitation, we devised a strategy based on editing the genomes of patient‐derived tumor organoids using CRISPR/Ca...
שמור ב:
| הוצא לאור ב: | EMBO Mol Med |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494503/ https://ncbi.nlm.nih.gov/pubmed/28468934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707550 |
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