Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells

30-40% of colorectal cancer (CRC) patients undergoing curative resection of the primary tumor will develop metastases in the following years(1). Therapies to prevent disease relapse remain an unmet medical need. Here we uncover the identity and features of the residual tumor cells responsible for CR...

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Publicado no:Nature
Main Authors: Cañellas-Socias, Adrià, Cortina, Carme, Hernando-Momblona, Xavier, Palomo-Ponce, Sergio, Mulholland, Eoghan J., Turon, Gemma, Mateo, Lidia, Conti, Sefora, Roman, Olga, Sevillano, Marta, Slebe, Felipe, Stork, Diana, Caballé-Mestres, Adrià, Berenguer-Llergo, Antonio, Álvarez-Varela, Adrián, Fenderico, Nicola, Novellasdemunt, Laura, Jiménez-Gracia, Laura, Sipka, Tamara, Bardia, Lidia, Lorden, Patricia, Colombelli, Julien, Heyn, Holger, Trepat, Xavier, Tejpar, Sabine, Sancho, Elena, Tauriello, Daniele V.F., Leedham, Simon, Attolini, Camille Stephan-Otto, Batlle, Eduard
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616986/
https://ncbi.nlm.nih.gov/pubmed/36352230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-022-05402-9
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