Nodal-induced L1CAM/CXCR4 subpopulation sustains tumor growth and metastasis in colorectal cancer derived organoids

Background: Colorectal cancer (CRC) is currently the third leading cause for cancer-related mortality. Cancer stem cells have been implicated in colorectal tumor growth, but their specific role in tumor biology, including metastasis, is still uncertain. Methods: Increased expression of L1CAM, CXCR4...

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Gepubliceerd in:Theranostics
Hoofdauteurs: Cave, Donatella Delle, Hernando-Momblona, Xavier, Sevillano, Marta, Minchiotti, Gabriella, Lonardo, Enza
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2021
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058729/
https://ncbi.nlm.nih.gov/pubmed/33897875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.54027
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