Genetic basis of variation in adenoma multiplicity in Apc(Min/+) Mom1(S) mice

Apc(Min) mice have provided an example of a locus (Modifier of Min1; Mom1) modifying adenoma numbers in the intestines of inbred strains. Linkage analysis located Mom1 on chromosome 4, and further investigation identified secretory phospholipase A2 (Pla2g2a) as a candidate gene. Because of unknown v...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Haines, Jackie, Johnson, Victoria, Pack, Kevin, Suraweera, Nirosha, Slijepcevic, Predrag, Cabuy, Erik, Coster, Margaret, Ilyas, Mohammad, Wilding, Jennifer, Sieber, Oliver, Bodmer, Walter, Tomlinson, Ian, Silver, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15710876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0500039102
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