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Identification of Mom12 and Mom13, two novel modifier loci of Apc(Min)-mediated intestinal tumorigenesis

Colorectal cancer is a heterogeneous disease resulting from a combination of genetic and environmental factors. The C57BL/6J (B6) Apc(Min/+) mouse develops polyps throughout the gastrointestinal tract and has been a valuable model for understanding the genetic basis of intestinal tumorigenesis. Apc(...

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Détails bibliographiques
Auteurs principaux: Crist, Richard C, Roth, Jacquelyn J, Lisanti, Michael P, Siracusa, Linda D, Buchberg, Arthur M
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100885/
https://ncbi.nlm.nih.gov/pubmed/21386660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.7.15089
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