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Identification of Mom12 and Mom13, two novel modifier loci of Apc(Min)-mediated intestinal tumorigenesis
Colorectal cancer is a heterogeneous disease resulting from a combination of genetic and environmental factors. The C57BL/6J (B6) Apc(Min/+) mouse develops polyps throughout the gastrointestinal tract and has been a valuable model for understanding the genetic basis of intestinal tumorigenesis. Apc(...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Landes Bioscience
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100885/ https://ncbi.nlm.nih.gov/pubmed/21386660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.7.15089 |
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