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Identification of the Modifier of Min 2 (Mom2) Locus, a New Mutation That Influences Apc-Induced Intestinal Neoplasia

Min (Multiple intestinal neoplasia) mice carry a dominant mutation in the adenomatous polyposis coli (Apc) gene and develop multiple adenomas throughout their intestinal tract (Moser et al. 1990; Su et al. 1992). Polyp multiplicity in Min mice is greatly influenced by genetic background. A modifier...

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Bibliografiske detaljer
Main Authors: Silverman, Karen A., Koratkar, Revati, Siracusa, Linda D., Buchberg, Arthur M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155250/
https://ncbi.nlm.nih.gov/pubmed/11779834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.206002
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