Diversity in secreted PLA(2)-IIA activity among inbred mouse strains that are resistant or susceptible to Apc(Min/+) tumorigenesis

The secreted phospholipase A(2) type IIA (Pla2g2a) gene was previously identified as a modifier of intestinal adenoma multiplicity in Apc(Min/+) mice. To determine if intestinal secreted phospholipase A(2) (sPLA(2)) activity was also attenuated in susceptible strains, we developed a sensitive assay...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Markova, Marina, Koratkar, Revati A, Silverman, Karen A, Sollars, Vincent E, MacPhee-Pellini, Melina, Walters, Rhonda, Palazzo, Juan P, Buchberg, Arthur M, Siracusa, Linda D, Farber, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002759/
https://ncbi.nlm.nih.gov/pubmed/16007193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208791
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