APC mutations are sufficient for the growth of early colorectal adenomas

It is not clear whether APC mutations are sufficient for early colorectal adenomas to grow or whether additional mutations at other loci are required. We previously have screened 210 early colorectal adenomas from familial adenomatous polyposis patients for mutations and allelic loss at APC. Here, w...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lamlum, Hanan, Papadopoulou, Angeliki, Ilyas, Mohammad, Rowan, Andrew, Gillet, Cheryl, Hanby, Andrew, Talbot, Ian, Bodmer, Walter, Tomlinson, Ian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040564697
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