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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

The insulin/insulin-like growth factor-like signaling pathway, present in all multicellular organisms, regulates diverse functions including growth, development, fecundity, metabolic homeostasis, and lifespan. In flies, ligands of the insulin/insulin-like growth factor-like signaling pathway, the Dr...

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Detalhes bibliográficos
Main Authors: Broughton, Susan J., Piper, Matthew D. W., Ikeya, Tomoatsu, Bass, Timothy M., Jacobson, Jake, Driege, Yasmine, Martinez, Pedro, Hafen, Ernst, Withers, Dominic J., Leevers, Sally J., Partridge, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549445/
https://ncbi.nlm.nih.gov/pubmed/15708981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405775102
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