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DILP-producing Median Neurosecretory Cells in the Drosophila Brain Mediate the Response of Lifespan to Dietary Restriction

Dietary restriction extends lifespan in diverse organisms but the gene regulatory mechanisms and tissues mediating the increased survival are still unclear. Studies in worms and flies have revealed a number of candidate mechanisms, including the TOR and insulin/IGF-like signalling (IIS) pathways, an...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Broughton, S.J., Slack, C., Alic, N., Metaxakis, A., Bass, T. M., Driege, Y., Partridge, L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467032/
https://ncbi.nlm.nih.gov/pubmed/20156206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00558.x
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