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DILP-producing Median Neurosecretory Cells in the Drosophila Brain Mediate the Response of Lifespan to Dietary Restriction

Dietary restriction extends lifespan in diverse organisms but the gene regulatory mechanisms and tissues mediating the increased survival are still unclear. Studies in worms and flies have revealed a number of candidate mechanisms, including the TOR and insulin/IGF-like signalling (IIS) pathways, an...

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Опубликовано в: :Aging Cell
Главные авторы: Broughton, S.J., Slack, C., Alic, N., Metaxakis, A., Bass, T. M., Driege, Y., Partridge, L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467032/
https://ncbi.nlm.nih.gov/pubmed/20156206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00558.x
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