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DILP-producing Median Neurosecretory Cells in the Drosophila Brain Mediate the Response of Lifespan to Dietary Restriction

Dietary restriction extends lifespan in diverse organisms but the gene regulatory mechanisms and tissues mediating the increased survival are still unclear. Studies in worms and flies have revealed a number of candidate mechanisms, including the TOR and insulin/IGF-like signalling (IIS) pathways, an...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Broughton, S.J., Slack, C., Alic, N., Metaxakis, A., Bass, T. M., Driege, Y., Partridge, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467032/
https://ncbi.nlm.nih.gov/pubmed/20156206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00558.x
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