The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.

Anti-Tac(Fv)-PE40 is a recombinant single-chain immunotoxin containing the heavy and light variable regions of the anti-Tac monoclonal antibody fused to a mutant form of Pseudomonas exotoxin (PE). Anti-Tac binds to the p55 subunit of the human interleukin 2 (IL-2) receptor, and anti-Tac(Fv)-PE40 kil...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kreitman, R J, Chaudhary, V K, Waldmann, T, Willingham, M C, FitzGerald, D J, Pastan, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2236041/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8291
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!