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Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region
Helper-dependent adenoviral vectors (HDAds) possess long homology arms that mediate high-efficiency gene editing. These long homology arms may permit simultaneous introduction of multiple modifications into a large genomic region or may permit a single HDAd to correct many different individual mutat...
שמור ב:
| הוצא לאור ב: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Gene & Cell Therapy
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493818/ https://ncbi.nlm.nih.gov/pubmed/28918012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.06.001 |
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