Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

O-linked N-acetylglucosamine (O-GlcNAc) is an essential and dynamic post-translational modification found on hundreds of nucleocytoplasmic proteins in metazoa. Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recogniz...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Rafie, Karim, Raimi, Olawale, Ferenbach, Andrew T., Borodkin, Vladimir S., Kapuria, Vaibhav, van Aalten, Daan M. F.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493779/
https://ncbi.nlm.nih.gov/pubmed/28659383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170078
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