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Dual functionality of O-GlcNAc transferase is required for Drosophila development

Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions. OGT possesses a C-terminal glycosyltransferase catalytic domain and N-terminal tetratricopeptide...

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Détails bibliographiques
Publié dans:Open Biol
Auteurs principaux: Mariappa, Daniel, Zheng, Xiaowei, Schimpl, Marianne, Raimi, Olawale, Ferenbach, Andrew T., Müller, H.-Arno J., van Aalten, Daan M. F.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703063/
https://ncbi.nlm.nih.gov/pubmed/26674417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150234
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