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Thio-Linked UDP–Peptide Conjugates as O-GlcNAc Transferase Inhibitors
[Image: see text] O-GlcNAc transferase (OGT) is an essential glycosyltransferase that installs the O-GlcNAc post-translational modification on the nucleocytoplasmic proteome. We report the development of S-linked UDP–peptide conjugates as potent bisubstrate OGT inhibitors. These compounds were assem...
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| Vydáno v: | Bioconjug Chem |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2018
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016062/ https://ncbi.nlm.nih.gov/pubmed/29723473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00194 |
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