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Role of Cyclic mPer2 Expression in the Mammalian Cellular Clock

To explore the role of mPer2 in the circadian oscillation in the mammalian cellular clock, we established fibroblast cell lines in which expression of mPer2 is controlled through a tetracycline-regulatable promoter. We revealed that constitutive expression and overexpression of mPer2 mRNA severely i...

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Autors principals: Yamamoto, Yoshinobu, Yagita, Kazuhiro, Okamura, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549376/
https://ncbi.nlm.nih.gov/pubmed/15713645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1912-1921.2005
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